1H-Indazole-4-methanamine, α-methyl-

1H-Indazole-4-methanamine, α-methyl- - Names and Identifiers

Name	1H-Indazole-4-MethanaMine, a-Methyl-
Synonyms	1-(1H-Indazol-4-yl)ethanaMine 1-(1H-Indazol-4-yl)ethanamine a-Methyl-1H-Indazole-4-methanamine 1H-Indazole-4-methanamine, α-methyl- 1H-Indazole-4-MethanaMine, a-Methyl-
CAS	1159511-31-5

1H-Indazole-4-methanamine, α-methyl- - Physico-chemical Properties

Molecular Formula	C9H11N3
Molar Mass	161.2
Melting Point	153 - 155o C
Boling Point
Solubility	DMSO (Slightly), Methanol (Slightly)
Appearance	Solid
Color	White to Off-White
Storage Condition	under inert gas (nitrogen or Argon) at 2–8 °C
Stability	Hygroscopic

1H-Indazole-4-methanamine, α-methyl- - Introduction

Alpha-methyl-lH-indazole-4-methylamine, also known as N-methylindoleamine, is an organic compound. Its chemical formula is C10H10N2, the structure contains the indole ring and methyl group.

This compound has the following properties:
1. Appearance: colorless to light yellow crystal
2. melting point: about 150-155 ℃
3. Boiling point: about 330-335 ℃
4. Solubility: Soluble in water and organic solvents, such as ethanol and dichloromethane

α-Methyl-1H-indazole-4-methylamine has a variety of uses, including:
1. Biochemical research: As a reagent, it is used to synthesize biologically active compounds, such as drugs and hormones.
2. Chemical synthesis: as an intermediate, it can be used to synthesize other organic compounds, such as dyes, fragrances and fluorescent dyes.
3. Insecticide: When combined with other compounds, it can be used as an insecticide in agriculture and horticulture.

The method for preparing α-methyl-1H-indazole-4-methylamine includes:
1. Nitro chemical method: it is prepared by the reduction reaction of nitroindole and then methylation reaction.
2. direct methylation reaction: the indole amine is reacted with a methylating agent, such as methyl sodium iodide or methyl sodium bromide.

Safety information when using and handling α-methyl-1H-indazole-4-methylamine:
1. Avoid contact with skin and eyes, which may cause irritation and burns.
2. During operation, appropriate protective measures should be used, such as laboratory gloves and goggles.
3. should be operated in a well-ventilated laboratory environment to avoid inhalation of its vapors.
4. Avoid exposing the compound to high temperatures or fire sources to prevent harmful gases and fires.
5. During storage and transportation, contact with oxidants and strong acids should be avoided to prevent dangerous reactions and accidents.

For specific safety information for chemical experiments or industrial applications, please refer to the relevant safety data sheet (Material Safety Data Sheet).

Last Update：2024-04-09 20:02:46